Clark's Botanicals
DNA-42 Clinicalift Serum
- Overview
- Choosing your shade
- How to use
- Ingredients
- Sustainable Packaging
- About the brand
Highlights
Suitable for
Normal, combination, dry, and mature skin seeking visible lift, resilience, and renewal.
Why we stand behind it
DNA-42 ClinicalLift Serum is a precision bioactive serum designed to visibly lift, firm, and restore skin’s structural integrity over time. Its weightless, fast-absorbing texture delivers immediate radiance on contact, while working beneath the surface to improve the look of firmness, elasticity, and resilience with continued use. At the core of the formula is the Collagen ProScaffolding Complex™, developed to support skin’s visible architecture and help maintain lift and density without heaviness or irritation. A high-concentration dual-PDRN and dual-exosome system further supports skin’s natural renewal signals, helping skin appear stronger, more energized, and visibly revitalized over time.
What distinguishes this serum is the intelligence behind how it is built. Developed through Clark’s Botanicals’ proprietary Amalfi-based regenerative biology platform, the formula reflects years of research into how skin responds to stress, recovery, and renewal through cellular communication rather than surface correction. Designed for both morning and night use, it layers seamlessly under moisturizer and makeup, delivering visible results without disruption.
This product embodies the Credo mission by proving that clean beauty can operate at the highest level of scientific sophistication. It prioritizes transparency, restraint, and long-term skin vitality, offering visible lift and glow without force, excess, or compromise.
Key ingredients
Dual PDRN Complex (plant-derived): Supports skin’s visible renewal signals to help improve the look of firmness, elasticity, and overall skin vitality with exceptional efficiency.
Dual Exosome System (botanical stem cells): Helps enhance cellular communication, allowing skin to appear smoother, more lifted, and more resilient in the face of daily stress.
Collagen Pro-Scaffolding Complex™: A proprietary structural support system designed to reinforce skin’s visible architecture, helping maintain lift, density, and definition without weight.
this product meets
The Credo Clean Standard™
Every product we offer meets our industry leading standards for safety and sustainability.
learn moreThis product is
Cruelty Free
Sustainable Packaging
Vegan
Gluten Free
Fragrance Free
Soy Free
Non GMO
What is an undertone?
An undertone is the color beneath the surface of your skin, which never changes (even with a tan). There are three types of undertones:
Pink/Cool
I see red or pink undertones around the perimeter of my face and neck.
My skin burns easily, but barely tans.
My skin looks better in silver jewelry than gold.
Neutral
I see both pink and yellow undertones around the perimeter of my face and neck.
My skin sometimes burns and sometimes tans.
My skin looks good in both gold and silver jewelry.
Yellow/Warm
I see yellow or golden undertones around the perimeter of my face and neck.
My skin rarely burns, but tans easily.
My skin looks better in gold jewelry than silver.
Find your shade match
Take our 1 minute quiz and get matched to real people with your skin tone and type.
Usage
Begin with clean, dry skin.
Dispense five to six drops of DNA-42 ClinicalLift Serum into the palm of your hand using the dropper.
Gently bring fingertips together to distribute the serum evenly.
Press into the skin, starting at the center of the face and moving outward, allowing the formula to absorb fully rather than massaging it in.
Extend application to the neck and décolleté using slow, upward motions.
Allow the serum to settle before layering moisturizer, sunscreen, or makeup.
Use morning and night to support visible lift, resilience, and radiance over time.
Pro-tip
Pro Tip 1: Give it 60 seconds. Don’t rush it.
After applying DNA-42 ClinicalLift Serum, wait a full 60 seconds before layering anything else. This isn’t about absorption. It’s about allowing the formula to establish skin’s tone and response before you add more variables. When you give it that minute, skin looks calmer, firmer, and noticeably more composed, and whatever follows sits with intention rather than effort.
Pro Tip 2: Press where skin moves, not where it’s flat
Use flat fingertips to gently press the serum into areas that show expression and movement the jawline, cheekbones, temples, and around the mouth. Skip rubbing. This mirrors how advanced formulas are applied in professional treatments and helps skin look more structured and awake. Makeup layered afterward appears smoother, wears longer, and breaks down less throughout the day.
Full ingredient list
Purified Water, Glycerin (plant-derived hydration), Acetyl Hexapeptide-8 (smoothing peptide), Palmitoyl Tripeptide-5 (firming peptide), Citrus Reticulata Extract (tangerine extract), Pistacia Lentiscus Gum (mastic resin), Sodium Hyaluronate (hyaluronic acid), Saccharide Isomerate (moisture binder), Aloe Barbadensis Leaf Extract (aloe vera), Helianthus Annuus Sprout Extract (sunflower sprout), Hydrolyzed Algin (marine polysaccharide), Plankton Extract (marine extract), Sodium DNA (PDRN complex), Hydrolyzed DNA (PDRN complex), Lycium Barbarum Callus Culture Extract (goji stem cells), Niacinamide (vitamin B3), Chondrus Crispus Extract (red algae), Hydrolyzed Rhodophyceae Extract (marine algae), Sea Water (marine minerals), Lecithin (phospholipids), Maltodextrin (plant carrier), Sucrose (natural sugar), Propanediol (plant humectant), Pentylene Glycol (skin humectant), Butylene Glycol (skin humectant), Phenethyl Alcohol (plant-derived), Glyceryl Caprylate/Caprate (plant emollient).
Fragrance
Overall impression: There is no added fragrance, yet you notice a soft, evolving scent as fresh, bioactive ingredients warm on the skin. It feels intimate and fleeting, more like an atmosphere than an aroma. The effect is reminiscent of skin after a facial, touched by air and light rather than perfume. Top notes: amalfi barley sprout, soft rice water, coastal green air Middle notes: jasmine stem brightness, living marine algae, sun-warmed botanicals Base notes: warm skin accord, gentle earthiness, mineral coastal breeze No added fragrance. These notes reflect the natural scent of the ingredients as they activate on the skin.
Help us end beauty packaging waste
We co-founded the nonprofit Pact to demystify how to recycle your beauty packaging empties and divert waste from landfills.
How to recycle your empties
1. Disassemble and clean all components
2. Pick the right disposal bin
3. Drop off your empties at your nearest Pact bin
1 Product Recycled = 10 Credo Rewards Points
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Clark's Botanicals
Skin that repairs itself. Clark’s Botanicals is a treatment-driven skincare system built on controlled renewal and longevity. Born from founder Francesco Clark’s experience healing compromised, reactive skin, the brand redefines performance: results should strengthen, not destabilize. Guided by our proprietary Amalfi research platform, we engineer regenerative, longevity-focused, barrier-intelligent formulas across five principles, the 5R System: Renew, Rebuild, Reset, Refine, and Rebalance. High-performance skincare for those seeking visible change with structural integrity and long-term skin strength.
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